Florkem

How to use

• 300mg/ml solution for intramuscular use
• 1 mL/15kg/ 48 hours apart

Withdrawal: cattle (meat) – 37 days, pigs (meat) 18 days

Prescription decisions are for the person issuing the prescription alone. Please refer to the product packaging and leaflets for information about side effects, precautions, warnings and contra-indications. Further information is available from the SPC or on the datasheet at www.noahcomendium.co.uk or on request.

Legal Category: UK POMV

SPC

Why choose
Florkem?

High syringeability

Florkem is easy to inject, even at low temperatures, reducing the chance of dosing errors and possible muscle trauma¹

Broad spectrum

Treatment of respiratory tract infections due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni susceptible to florfenicol

Fast acting

Therapeutic concentrations in florfenicol are reached within 30 minutes in blood and less than 2 hours in lungs after injection²

Marked reduction in rectal temperature observed within 24 hours³

Hi-tech CLAS vial

In a shock-resistant vial, resulting in fewer
breakages if dropped⁴

Ergonomically designed⁵ and are light-weight for ease of handling⁶

Supports the responsible use of antibiotics

Not used for the treatment of humans and not classified as critically important antibiotic^7,8

Recent European data reported no change in the
very high susceptibility in target pathogens⁹

References

1. Manteca C, Lacoste S, Riboud C, Remmy D (2011) Comparison of injectability of 4 different formulations of florfenicol. European Buiatrics Forum, Marseille. 189.

2. Varma KJ (1994) Microbiology, pharmacokinetic disposition and safety of florfenicol in cattle in Proceedings International Symposium on Bovine Respiratory Disease. World Buiatrics Congress, Toulouse, 18-24.

3. Thiry J, Rubion S, Sarasola P, Bonnier M, Hartmann M, de Haas V. (2011) Efficacy and safety of a new 450 mg/ml florfenicol formulation administered intramuscularly in the treatment of bacterial bovine respiratory disease. Vet. Rec. Nov 12;169(20):526

4. Cavaroc P. J. et al. Comparative breakage study of injectable anti-infectives vials under vertical drop test by free fall under standardized conditions. IPVS Congress, 2012, 100

5. CLAS vials reference book (2012). Section 5.2: Artis Factis and Ceva developed hand zone ergonomic study (2003). P16

6. CLAS vials reference book (2012). Section 5.4: Comparison of the weight of CLAS vials vs. glass vials showing that CLAS vials are 6 X lighter than glass vials of the same size. P19

7. WHO Critically important antimicrobials for human medicine, 5th revision. 2017

8. EMA Antimicrobial Resistance in Veterinary Medicine. https://www.ema.europa.eu/en/veterinary-regulatory/overview/antimicrobial-resistance-veterinary-medicine

9.Andres-Lasheras et al. 2019. Serotyping and antimicrobial resistance of Mannheimia haemolytica strains from European cattle with bovine respiratory disease. Res Vet Sci 124:10-12

1. Manteca C, Lacoste S, Riboud C, Remmy D (2011) Comparison of injectability of 4 different formulations of florfenicol. European Buiatrics Forum, Marseille. 189. 2. Varma KJ (1994) Microbiology, pharmacokinet ...